KDM1A and cancer: Histone demethylase LSD1 (also referred to as KDM1A, AOF2, BHC110 or KIAA0601) was the first identified histone demethylase and is a member of the flavin adenine dinucleotide (FAD)-dependent amine oxidase family of demethylases.15 LSD1 inhibitors are a hot topic in the field of cancer therapy.23,24,42 However, few studies have investigated the effects of LSD1 inhibitors on the osteogenic differentiation of BMMSCs.