The moderate to severe increase associated with other changes in the MS group such as dyslipidemia and elevated blood glucose, and probably resistance insulin, may contribute to the development of complications associated with hypertension including stroke (CVA), retinopathy, choroidopathy, ventricular hypertrophy, albuminuria/microalbuminuria, and nephropathy [12, 17]. The gene discussed is INS; the disease is hypertensive disorder.