In this work, to analyse the expression patterns of ALS1–ALS3, HWP1, SAP1, SAP4–SAP6, LIP1–LIP10, PLB1-PLB2, CDR1, and MDR1, we implemented an in vitro model of infection of human vaginal cells with C. albicans strains isolated from women with VVC. This evidence concerns the gene PLB1 and infection.