In support of this, genetic analysis of people with CMM have identified mutations in Deleted in Colorectal Cancer (DCC)5, 14, 15, a receptor for Netrin-1, which is an axon guidance molecule known to be important for midline guidance decisions during development, including decussation of the CST and CC16, 17 as well as neuronal branching and filopodia formation of the axons that form these tracts18. Here, DCC is linked to familial congenital mirror movements.