AFP and neoplasm: The AUROC for prediction of microvascular invasion based on MVI index (Fig. 1d) was 0.743 (SE 0.039), significantly higher than each of those observed for the three independent predictors: pre-transplant alpha-fetoprotein (p = 0.002), number of tumors (p = 0.022), and size of the largest tumor (p = 0.001).