Due to the species selectivity of bevacizumab (i.e., only the influence of the tumor-derived VEGF would have been inhibited in these experiments, and the mouse stromal cell-derived VEGF would have been unaffected), we also investigated the effect of the small molecule inhibitor of the VEGFR2 receptor sunitinib in an attempt to block all VEGFR signaling. The gene discussed is KDR; the disease is neoplasm.