Moreover, previous studies have suggested the active involvement of VEGF in the pathogenesis of asthma, which may be mediated by 1,25-dihydroxycholecalciferol [1,25(OH)2 D3], the active form of vitamin D. In addition, 1,25(OH)2D3 has also been shown to inhibit the proliferation of airway smooth muscle cells [6]. Here, VEGFA is linked to asthma.