Cox proportional-hazards regression analysis of DSS was performed, with adjustment for the following clinical variables shown to be prognostic factors on univariate analysis: age (≥65 vs. <65), main location (middle or lower vs. upper), depth of tumor invasion, lymph-node metastasis, and FGFR1, FGFR2, and FGFR4 expression (low vs. high). This evidence concerns the gene FGFR2 and neoplasm.