High expression levels of FGFR1, 2, and 4 were significantly associated with the depth of invasion (early cancer vs. advanced cancer), lymph-node metastasis (negative vs. positive), tumor stage (stage I vs. stage II or more advanced), and distant metastasis or recurrence (negative vs. positive). This evidence concerns the gene FGFR1 and metastatic malignant neoplasm in the lymph nodes.