Amplification of the FGFR1 gene was a rare but noticeable event that was found in 2% (6 of 293) of GCs and was associated with distant metastasis and poor survival in another study, although tumors with FGFR1 amplification were found in IGC, DGC, and mixed-type GC [34]. The gene discussed is FGFR1; the disease is gastric cancer.