AFP and neoplasm: Recently, Xu et al. studied a large cohort of Chinese HCC patients and stratified patients fulfilling the Hangzhou criteria into type A (tumor burden ≤8 cm or tumor burden >8 cm, but with AFP ≤100 ng/mL and well to moderate differentiation) and type B (tumor burden >8 cm, but AFP between 100 and 400 ng/mL and well to moderate differentiation).