It has been suggested by others that MBL deficiency also plays a role in several non-infectious diseases such as systemic lupus erythematosus [24], type 2 diabetes mellitus [25], cystic fibrosis [26], rheumatoid arthritis [27] and Crohn’s disease [28]. Here, MBL2 is linked to hyperinsulinemic hypoglycemia, familial, 4.