However another phase II study including both BRCA mutant and wild type patients with breast cancer and HGSOC showed encouraging activity also in the cohort of wild type, platinum-sensitive HGSOC patients [46], likely due to the acquired defects of HR genes responsible for “BRCA-like phenotype”, which conferred the same sensitivity to both platinum-chemotherapy and PARP inhibition. Here, PARP1 is linked to breast cancer.