A detailed analysis of expression levels of each PHF in the five breast cancer subtypes also revealed that expression levels of PYGO2 and KDM5B were higher in Luminal, HER2+, and basal-like, compared with their expression levels in the normal-like subtype of breast cancer (Figure 1, Supplementary Figure S3, and Supplementary Table S5). This evidence concerns the gene KDM5B and breast carcinoma.