RNA isolated from 3 independent AD and CR LuCaP35.1 lesions were analyzed by RNA-seq and then compared to genes i) regulated by Src in LNCaP[Src527F] cells (Figure 7C), ii) regulated in CRPC vs. primary PC lesions from the Sharma et al. group [46](Figure 7D), and iii) near AR binding sites in CRPC samples (Figure 7E). Here, SRC is linked to pachyonychia congenita.