NFKB1 and Alzheimer disease: Interestingly, when the three CR LuCaP35.1 samples were compared to the AD samples, the genes most differentially upregulated in the CR lesions were almost all interferon-inducible (Supplementary Figure 13A), possibly reflecting increased NFkB-regulated survival pathways in CR cells in response to recruited, pro-metastatic inflammatory cells [84].