Because an active CXCL12/CXCR4 signaling pathway has been shown to mediate tumor cell proliferation, survival and migration in several tumor types including MPNSTs [6, 11, 12] and BH3 mimetics have been demonstrated to modulate CXCL12 transcription [28, 33], we sought to assess CXCL12 mRNA levels in T265-2c cells treated with AT101 (5μM for 24h) by quantitative real time PCR. This evidence concerns the gene CXCR4 and neoplasm.