Breast cancer is one of this kind of cancer.11, 12, 13, 14 Previous reports have elaborated that miRNAs are involved in various essential cellular processes of breast cancer, such as proliferation,15 apopotosis,16 stem-cell renewal,17 EMT18 and metastasis.19 In our previous study, we demonstrate that miR-124 has an important role in breast cancer invasion-metastasis cascade by targeting EMT regulator Slug20 and miR-630 suppresses breast cancer progression by targeting metadherin.21 The gene discussed is MTDH; the disease is breast carcinoma.