Interestingly, Hb chains have been found highly induced by low iron diet in the ventral midbrain of adult mice, implicating them in brain iron homeostasis, a pathway involved in PD as well.50 On the other hand, it will be interesting to assess the relationship, if any, of Hb levels in blood and DA cells in normal and pathological conditions of hematological origin, such as thalassemia. The gene discussed is GSTM1; the disease is thalassemia.