PTGS2 and breast cancer: This results were further confirmed using 4538 breast cancer patient cohort in Breast Cancer Gene-Expression Miner v4.0 database which also revealed a significant higher expression of COX-2 mRNA levels in TNBC tumors compared to non-TNBC tumors (P = 0.0001) (Fig. 1g) and in the more aggressive basal-like subtype of TNBC compared to non-basal-like tumors (Fig. 1h).