PTGS2 and breast cancer: We first analyzed the COX-2 expression levels in various breast cancer subtypes using GOBO (http://co.bmc.lu.se/gobo) online tool in a large dataset (1,881 patients) of breast cancer patients28 as well as the Breast Cancer Gene-Expression Miner v4.0 (bc-GenExMiner v4.0) database including 5609 breast cancer patients29.