After validating that KCNAB2 (Fig. 1c) and KCNIP1 (Supplementary Fig. 1) proteins indeed directly bound NEAT1 in the neuroblastoma cell-line SH-SY5Y by native RNA immunoprecipitation, we found that activation of SH-SY5Y cells by depolarization with 50 mM KCl results in a significant and transient cytoplasmic enrichment of KCNAB2 (Fig. 1d) with a corresponding significant nuclear decrease (Supplementary Fig. 2a) and a significant reduction in NEAT1 transcript after 1 and 3 hours (Supplementary Fig. 2b). This evidence concerns the gene KCNIP1 and neuroblastoma.