IAPP and type 2 diabetes mellitus: Pancreatic amyloid deposits in human, comprised of islet amyloid polypeptide (hIAPP, a 37-amino acid residue polypeptide chain, also known as Amylin), are found in more than 95% of T2DM patients and toxicity caused by them is believed to be a major reason for the pancreatic-β-cell dysfunction and pathogenesis of the diseasse6, 7, 8.