Since NLRP3 is detectable in many cardiac cell types, including cardiofibroblasts (the most important cell type in the heart in terms of number of cells) and cardiomyocytes (the most important cell type in terms of cell volumes), it is likely that it may play a pivotal role in acute myocardial infarction [10, 11]. The gene discussed is NLRP3; the disease is myocardial infarction.