Since NLRP3 is detectable in many cardiac cell types, including cardiofibroblasts (the most important cell type in the heart in terms of number of cells) and cardiomyocytes (the most important cell type in terms of cell volumes), it is likely that it may play a pivotal role in acute myocardial infarction [10, 11]. This evidence concerns the gene NLRP3 and acute myocardial infarction.