For principal component 1 described by 19% of the variation, 12 variables showed loadings higher compared to the established threshold, translated into a strong relationship between immune reactivity to the MAP peptides, presence of MAP DNA, IBD history within family, Asacol treatment, consumption of fast food meals and clinical symptoms such as bloody stool, low Hb and weight loss; an inverse association was observed among variables related to age, consumption of fruit and vegetables and duration of breastfeeding period. This evidence concerns the gene GSTM1 and inflammatory bowel disease.