CD8A and systemic lupus erythematosus: Further detection of LC3IIB by flow cytometry also indicated higher basal autophagic activity in SLE patients in comparison to healthy controls (6.69 ± 0.23 versus 4.31 ± 0.13, p < 0.0001 for CD3+T cells; 5.25 ± 0.22 versus 3.58 ± 0.07, p = 0.0001 for CD4+T cells; 7.52 ± 0.26 versus 5.01 ± 0.09, p < 0.0001 for CD8+T cells) (Figure 2).