SPARC and gastric cancer: High SPARC expression was highly correlated with reduced OS (pooled HR = 1.60, 95% confidence interval (CI): 1.01–2.53, transformed from lnHR and its 95% CI; Figure 4A), and the further chronologically cumulative meta-analysis demonstrated that our current study enhanced the combining effect favoring the prognostic role of SPARC in GC (pooled HR = 1.59, 95% CI: 1.12–2.23, transformed from lnHR and its 95% CI; Figure 4B).