The relation between hypertension and myocardial infarction could be explained underscoring two key factors: (1) common risk factors, such as sympathetic hyperactivity, insulin resistance, vasoactive substances (i.e., angiotensin II), and genetic risk profiles and (2) hypertension is a risk factor of atherosclerosis, which contributes to progression of myocardial infarction [62]. The gene discussed is AGT; the disease is hypertensive disorder.