As the receptor tyrosine kinase (RTK) Fibroblast Growth Factor Receptor (FGFR) 2 is a known splicing target of ESRP1 and is highly expressed in some CRC cell lines, we investigated whether the FGFR pathway was involved in the activation of Akt in the ESRP1-overexpressing cells [23,26]. This evidence concerns the gene AKT1 and colorectal carcinoma.