ESRP1-induced changes, such as Snail expression, did not affect liver colonisation of CRC cells as reflected by similar number of micrometastases generated by ESRP1-overexpressing and Empty control COLO320DM cells, hence supporting the data showing that Snail is dispensable for metastasis, as occurs in pancreatic cancer [46]. The gene discussed is SNAI1; the disease is colorectal carcinoma.