The median plasma cfDNA concentrations of the 93 tumor-tissue EGFR M+ and 122 tumor-tissue EGFR M- patients were 9.61 ng/mL (range 1.01-406.91) and 12.82 ng/mL (range 1.32-2302.22), respectively; this difference was statistically significant (P = 0.049) (Figure 2A). The gene discussed is EGFR; the disease is neoplasm.