EGFR and neoplasm: Among the 114 patients treated with EGFR-TKIs, 80 (70.1%) were positive for tumor-tissue TKI-sensitizing EGFR mutations, including 45 Exon 21 L858R mutations, 33 Exon 19 del mutations, 1 Exon 19 del and Exon 18 G719X mutation, and 1 Exon 18 G719X mutation, whereas 32 (28.1%) were negative for tumor-tissue EGFR mutations and 2 (1.8%) were TKI-resistanting EGFR mutations(1 Exon 21 L858R/Exon 20 T790M mutation and 1 Exon 20 insertion mutation).