Nine ccRCC tissues (one VHL wild-type, two with mutation Leu158Val (#1, #2), one with Arg161Gln, one with Cys162Arg, one with Arg161Pro, one with Tyr98Asn and two with Arg161X (#1, #2)) and three normal kidney tissues were investigated for RNA expression of VHL, TP53 and its downstream targets. The gene discussed is TP53; the disease is nonpapillary renal cell carcinoma.