Compared with NGT group, patients with T2DM showed higher BMI, FPG, HbA1c, TC, triglyceride (TG), low density lipoprotein cholesterol (LDL-C), and FINS levels when compared to control, while T2DM group showed lower high density lipoprotein cholesterol (HDL-C), insulin sensitivity index (ISI), and HOMA-β which is function index of β-cell and index of insulin resistance (IR) levels. The gene discussed is INS; the disease is type 2 diabetes mellitus.