Investigating molecular mechanisms of baicalein treatment was not within the scope of this descriptive study, but Bhattacharya et al. showed that skeletal muscle atrophy (during aging and neurodegenerative diseases) can be diminished with inhibition of 12-LOX and 15-LOX, while the activation of this pathway led to increased NADPH oxidase activity, protein ubiquitination, and proteolytic degradation. The gene discussed is ALOX12; the disease is neurodegenerative disease.