EIF2S1 and malaria: The differentially expressed genes up-regulated by the MEL treatment included E3 ubiquitin ligase (PF3D7_0704600); regulator of initiation factor 2 (eIF2; PF3D7_0322400), which plays an important role in post- transcriptional control of gene expression in malaria parasites; and the gene encoding S-adenosylmethionine decarboxylase/ornithine decarboxylase (AdoMetDC/ ODC; PF3D7_1033100).