The BCR-ABL1 fusion genes resulted from the translocation of t(9;22)(q34;q11) or Philadelphia Chromosome (Ph+) are found in virtually all chronic myelogenous leukemia (CML), one third of adult lymphoblastic leukemia (ALL), and occasionally in acute myeloid leukemia (AML) [1-2]. The gene discussed is ABL1; the disease is acute myeloid leukemia.