TP53 and breast carcinoma: On the other hand, Gabriel et al. [38] studied leucurolysin B (leukocyte-B), which is a P-metalloproteinase class III isolate of B. leucurus in tumor cell lines T98 (p53 mutant malignant glioblastoma), U87 and RT2 (wild-type p53 malignant glioblastoma), MCF7 (breast carcinoma), EAC (Ehrlich ascites carcinoma), and UACC (melanoma) and viewed the chromatin condensation and nuclear fragmentation by DAPI staining, with results similar to ours.