This screening has shown that concentrations of 15 biomarker proteins (IL-1α, IL-1β, IL-6, IL-8, IL-12p40, IL-13, G-CSF, MCP-1, MIP-1α, MIP-1β, IFN-α, TNF-α, EGF, VEGF, and TNF-RII) were significantly higher in patients with resected high-risk melanoma compared with healthy controls. This evidence concerns the gene CCL3 and melanoma.