CXCL8 and Cachexia: From this profile, when compared to that of the control group, it appears that serum levels of all cytokines were significantly higher in the cachexia group, and six cytokines (IL-1β, IL-2, IL-8, IL-12, TNF-α, and IFN-γ) were significantly higher in the group with advanced Pca without cachexia.