IL6 and Familial prostate cancer: On the other hand, in a study of the pathophysiology of cachexia in patients with prostate cancer, a serum cytokinome profile of 10 biomarkers (IL-1β, IL-2, IL-4, IL-5, IL-6, IL-8, IL-10, IL-12, IFN-γ, and TNF-α) was evaluated.