PAFr and TLR2 are known to interact with intact pneumococci and purified pneumococcal peptidoglycan-teichoic acid complex (cell wall [CW]) on human brain microvascular endothelial cells (HBMEC) and human adenocarcinoma lung epithelial cells (A549) (7, 12). The gene discussed is PTAFR; the disease is adenocarcinoma.