DZANK1 and posterior polymorphous corneal dystrophy: In the PPCD mouse, a chromosomal inversion flanked by deletions involving Csrp2bp and Dzank1 has been identified in the portion of chromosome 2 that is syntenic to the human PPCD1 locus.[28, 29] The investigators reported the upregulation of two Csrp2bp fusion transcripts and Ovol2, which is located 37 kb from Csrp2bp and 66 kb from the breakpoint of the chromosomal inversion.