In the current study, analysis of the allele frequencies of TLR9 SNPs showed that A (rs352139) and T (rs352140) alleles were detected more frequently in children with HCMV infection than in uninfected individuals (permutation values P = 0.003 and P = 0.03, respectively; Table 5). The gene discussed is TLR9; the disease is cytomegalovirus infection.