Multiple-SNP analysis showed that the most common haplotype for the TLR3 SNPs rs3775290, rs3775291, rs3775296 and the TLR7 SNPs rs179008 and rs5741880 was CCCAT (21.5% for uninfected cases) and CTCAG (20.6% for children with HCMV infection). This evidence concerns the gene TLR3 and cytomegalovirus infection.