Two of them were described before: DSP variant as unclassified in proband with arrhythmogenic right ventricular cardiomyopathy [13] and MYH7 variant as possibly pathogenic but coexisting with another possibly pathogenic variant in LDB3 gene in proband with familial dilated cardiomyopathy [12]. Here, LDB3 is linked to familial dilated cardiomyopathy.