To summarize, TCV was associated with remissions in clinical symptoms and reductions in SLEDAI and anti-ds-DNA antibodies and GC doses and increases in C3 and C4 levels, with no pathogenic side effects during treatment and follow-up, which may prove TCV functions effectively and safely in alleviating and regulating the manifestation of SLE patients. The gene discussed is C4A; the disease is systemic lupus erythematosus.