DNM1L and Parkinson disease: For example, hiPSC-derived neurons obtained from patients affected by Parkinson's [188] and Huntington's [189] diseases exhibited deregulation of the peroxisome proliferator-activated receptor c coactivator 1 (PGC-1α) and dynamin-related protein 1 (DRP1) pathways, involved in mitochondrial fusion and fission, respectively.