The present study suggested that PECGGp had cardioprotective effects against myocardial infarction and heart failure, and the cardioprotective effects may be associated with increment of endogenous antioxidants, sustained antioxidant status in myocardial infarction, elevation of NO, eNOS, and SOD3 levels, and reduction in MDA. Here, NOS3 is linked to myocardial infarction.