One study reported CCL24 and VEGFA synchronously increased in 370 genes analysis of atopic dermatitis disease, one kind of chronic inflammatory skin disease [29]; whereas patients with myalgic encephalomyelitis/chronic fatigue syndrome appeared opposite outcome, VEGFA was reduced along with increases of CCL24 concentrations in plasma levels [30]; and In AMD disease, Takeda found the cause of choroidal neovascular endothelial cells drove from the trafficking of CCL24 to its downstream CCR3 [18]. The gene discussed is CCR3; the disease is myalgic encephalomeyelitis/chronic fatigue syndrome.