Certainly, the study of cancer-related inflammation enhancing tumor cell survival, proliferation, and metastasis has flourished over the last few decades, however, the role of CCL24 in HCC has not been investigated, considering liver is homologous with the gut in embryonic development, there was an urgent need to investigate CCL24 expression in HCC as well as its potential contribution to the inflammatory microenvironment in HCC [7]. The gene discussed is CCL24; the disease is cancer.