Moreover, DM patients with MetS had higher body fat mass (P < 0.001), HbA1c level (P = 0.007), BUN (P = 0.020), hs-CRP (P < 0.001), insulin level (P < 0.001), HOMA-IR (P < 0.001), and lower GFR (P = 0.021). Here, INS is linked to metabolic syndrome.