SCHLAP1 and Familial prostate cancer: For example, in prostate cancer of human, lncRNA SChLAP1 and chromatin remodelling complex SWI/SNF have opposing roles. SchLAP1 has an interaction with the SNF5 subunit of SWI/SNF and inhibits binding of SWI/SNF to chromatin, which leads to genome-wide derepression of gene activity [11].