The diagnosis of non-obstructive azoospermia was based on the following examinations: normal semen volume, normal testicular size, presence of the vas deferens by clinical examination, normal levels of serum follicle-stimulating hormone (FSH), azoospermia, absence or low levels of fructose and absence of spermatozoa in sample extracted by percutaneous testicular sperm aspiration (TESA). This evidence concerns the gene BRD2 and Azoospermia.