Moreover, survivin knockdown was associated with a decreased tumor weight when compared with controls [NEC-DUE1: 0.05 g (± 0.01) versus 0.15 g (± 0.02), p = 0.014; NEC-DUE2: 0.34 g (± 0.05) versus 0.58 g (± 0.09), p = 0.016) (Supplementary Figure 2C and 2D). This evidence concerns the gene BIRC5 and neuroendocrine carcinoma.