BIRC5 and neuroendocrine carcinoma: This was characterized by a reduced average tumor volume in the survivin knockdown tumors when compared with control tumors at study termination [NEC-DUE1: 78.3 mm3 (± 11.68) versus 283.4 mm3 (± 95.43), p = 0.023; NEC-DUE2: 375.6 mm3 (± 62.65) versus 745.0 mm3 (± 131), p = 0.008] (Figure 2D).