However, the CK+CTCs (CK+/Vimentin-/CD45-CTC plus CK+/Vimentin+/CD45-CTC) subset alone cannot distinguish metastatic from non-metastatic disease (15.24±12.72 vs 10.28±5.076cells/mL; P=0.3977) (Figure 7B). Here, VIM is linked to metastatic neoplasm.