Overall, the pooled analysis demonstrated a significant, negative association between the NFKB1 -94ins/delATTG polymorphism and overall cancer risk under all five genetic models (described in the Materials and Methods section): DD vs. II: OR = 0.75, 95% CI = 0.64-0.87; ID vs. II: OR = 0.91, 95% CI = 0.83-0.99; DD vs. ID/II: OR = 0.81, 95% CI = 0.71-0.91; ID/DD vs. II: OR = 0.86, 95% CI = 0.78-0.95; and D vs. I: OR = 0.88, 95% CI = 0.81-0.95. The gene discussed is NFKB1; the disease is cancer.