CD274 and metastatic malignant neoplasm in the lymph nodes: In patients without lymph node metastasis, the tumoral PD-L1 expression (≥1%, 5%, 10%, 20%, or 30% as cut-off value) was associated with improved DFS (P=0.026, 0.024, 0.015, 0.003, or 0.005) and OS (P=0.019, 0.015, 0.016, 0.007 or 0.011) (Figure 3), however, stromal expression was non-significant in the assessment of association with survival (Supplementary Table 6).