CD274 and metastatic malignant neoplasm in the lymph nodes: Upon univariate analysis, stage, lymph node metastasis, vascular involvement, depth, and tumoral PD-L1 expression (≥10%, 20% or 30%) were associated with DFS, and on multivariate analysis, stage, lymph node metastasis and tumoral PD-L1 expression (≥10%, 20% or 30%) were associated with DFS (Table 2).