The 2.8MM probe-CMA test was particularly useful in individuals who harbor a pathogenic CNV in regions covered by the custom probes contained on that CMA to optimize clinical interpretation in cases of DD, ASD and ID, including but not limited to the genes for GAMT deficiency (GAMT) and congenital Rett syndrome (FOXG1-related disorder). This evidence concerns the gene GAMT and hyperinsulinemic hypoglycemia, familial, 4.