Moreover, colorectum-specifically expressed genes, such as carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5), lectin, galactoside-binding, soluble, 4 (LGALS4), mucin 13 (MUC13), and calpain 5 (CAPN5), were moderately expressed in both CRC and STAD, suggesting that a group of organ-specific genes disobeyed tissue-specificity (or, more accurately, tumor-specificity). This evidence concerns the gene CAPN5 and colorectal carcinoma.